I have found that tuning my guitar low to high E F# B E B E (this covers two octaves) provides me not only with a unique sound but I can improvise on the 2nd, 3rd, 4th, and 5th strings and learn songs that I could not learn using the conventional tuning. You may want to capo up a couple of frets to make it sound more natural.
Gman Original, I think...